Alprostadil 745-65-3 Hormone uye endocrine
Kubhadhara:T/T, L/C
Kwakabva Chigadzirwa:China
Shipping Port:Beijing/Shanghai/Hangzhou
Kukwanisa kugadzira:1kg/mwedzi
Order(MOQ): 1g
Nguva Yekutungamira:3 Mazuva Ekushanda
Mamiriro ekuchengetedza:ine ice bag yekufambisa, -20 ℃ yekuchengetedza kwenguva refu
Package zvinhu:vial, bhodhoro
Pakeji saizi1g/bhodhoro, 5/mubhodhoro, 10g/mubhodhoro, 50g/bhodhoro, 500g/bhodhoro
Mashoko ekuchengetedza:UN 2811 6.1/PG 3
Nhanganyaya
Alprostadil, inonziwo Prostaglandin E1 kana PEG1.Inowanikwa zvakanyanya mumuviri webiologically inoshanda zvinhu, seimwe yemhuri yeprostaglandin, inozivikanwa endogenous physiologically active substance.
Inogona kushandiswa zvakananga pavascular smooth muscle, kuderedza mitsipa yeropa uye kuwedzera kuyerera kweropa, izvo zvinogona kuvandudza microcirculation perfusion.Inogona kuvharidzira kuunganidzwa kweplatelet uye thromboxane A2 kugadzirwa, pamwe nekudzivisa atherosclerosis, lipid plaque uye immune yakaoma kuumbwa.
Iyo zvakare ine zvinotevera zvinokonzeresa: kuwedzera kweiyo periphery tsinga diki dzeropa uye coronary arteries, kuderedzwa kweperipheral vascular resistance uye blood pressure.Kudzivirira platelet membrane iyo inogona kurwisa thrombosis.Kuchengetedza ischemic myocardium, iyo inogona kuderedza myocardial infarct size.Inoshandiswa kurapa anti-moyo kutadza zvakare.Iine diuretic uye renal-protecting function, yakavakirwa pakuwedzera renal tsinga yeropa kuitira kuwedzera renal kuyerera kweropa.Munguva iyi, inogona kubvisa isiri-protein nitrogen, uye kugadzirisa sodium nemvura.
Zviri kuchipatara kushandiswa kwakawanda.Zvakadai sekunetsekana kwechirwere cheshuga, chirwere chemoyo chemoyo uye kutadza kurongeka kwemoyo.Zvakare kushandiswa pamamiriro ezvinhu senge congenital moyo chirwere chakaomeswa nepulmonary hypertension, cerebral infarction uye chisingaperi arterial occlusive chirwere.Kune zvimwe zviitiko sekungoerekana matsi, retinal tsinga kuvharika, hutachiona hepatitis kana chisingaperi gastritis, inewo basa.Inogona kushandiswa kuchipatara pane zvimwe zvirwere zvakadai seduodenal ulcer, chronic renal insufficiency uye pancreatitis.Iko kushandiswa mukusimwa kwenhengo.Inoshandiswa kune zvimwe zvirwere zvakadai se erectile dysfunction, labour induction uye postpartum hemorrhage, femoral head necrosis, lumbar disc herniation, postherpetic neuralgia uye bronchial asthma.
Inofanirwa kuchenjerera kushandiswa kune varwere vane chirwere chakafanana nekutadza kwemoyo, glaucoma, peptic ulcer kana interstitial pneumonia.Nezvinogumbura mhedzisiro kune tsinga, icharatidza zviratidzo zvekuzvimba sekutsvuka, kuzvimba, kupisa uye kurwadziwa, izvo zvinogona kukonzera phlebitis.Inofanirwa kumira kuti ishandise kuchengetedza kana pane mamiriro ezvinhu.
Tsanangudzo (USP43)
| Item | Tsanangudzo |
| Chitarisiko | Ichena kana kuti yero zvishoma yecrystalline poda |
| Identification | IR |
| Residue pakubatidza | ≤0.5% |
| Muganhu wechromium | ≤0.002% |
| Muganhu werhodium | ≤0.002% |
| Zvinhu zvinoenderana | Prostaglandin A1 ≤1.5% |
| Prostaglandin B1 ≤0.1% | |
| Chero kusachena kwekunze kweprostaglandin kunobuda pamberi peprostaglandin A1 ≤0.9% | |
| Kusachena panguva yekuchengetedza nguva 0.6, maererano neprostaglandin A1 ≤0.9% | |
| Huwandu hwekusachena panguva dzekuchengetedza nguva 2.0 uye 2.3 ≤0.6% | |
| Chero imwe kunze kwekunze kweprostaglandin kusachena kunobuda mushure me prostaglandin A1 ≤0.9% | |
| Yese tsvina ≤2.0% | |
| Kutsunga kwemvura | ≤0.5% |
| Residual solvents | Ethanol ≤5000ppm |
| Acetone ≤5000ppm | |
| Dichloromethane ≤600ppm | |
| N-Hexane ≤290ppm | |
| N-Heptane ≤5000ppm | |
| Ethyl acetate ≤5000ppm | |
| Assay (pane anhydrous basis) | 95.0%~105.0% |
