Amphotericin B 1397-89-3 Antibiotic
Kubhadhara:T/T, L/C
Kwakabva Chigadzirwa:China
Shipping Port:Beijing/Shanghai/Hangzhou
Kukwanisa kugadzira:100kg / mwedzi
Order(MOQ):25kg
Nguva Yekutungamira:3 Mazuva Ekushanda
Mamiriro ekuchengetedza:ne ice bag rekutakura.Chengetedza pa2-8 ℃ kwenguva refu.
Package zvinhu:ngoma
Pakeji saizi25kg / chigubhu
Mashoko ekuchengetedza:Kwete zvinhu zvine ngozi
Nhanganyaya
Amphotericin B, inogona kudaidzwa kuti Fungizone kana Ambisome, iri polyene antifungal antibiotic yakaparadzaniswa netsika yeStreptomycesnodosus.Yakaparadzaniswa nezvikamu zviviri zvine A uye B, asi A chikamu chishoma basa reantifungal risingashandiswe, saka vanhu vanoshandisa B chikamu chinodaidzwa kuti Amphotericin B.
Iyo antifungal mishonga inoshandiswa kune yakakomba fungal utachiona uye leishmaniasis.Iine maviri akasiyana kushandiswa nemuromo uye jekiseni.
Amphotericin B ndiyo sarudzo yekutanga kune yakadzika fungal utachiona nekuda kwehupamhi hwehutachiona hwehutachiona.Iine inhibit basa kune fungals se cryptococcus, coccidium, candida albicans uye blastomycetes, etc. Ichauraya fugal panguva yepamusoro, inova mushonga unoshanda wekurapa kwakadzika fungal utachiona.
Makiriniki makuru anoratidza se: 1. Kurapa kwefungals se cryptococcosis, North America blastomycosis, kuparadzirwa candidiasis, coccidiosis uye histoplasmosis.2. Kurapa kwemucormycosis kunokonzerwa nedzimwe fungals seRhizopus, colporium, endomycetes uye datya fecal mold.3. Kurapa kwesporotrichosis kunokonzerwa nesporotrichosis schenckii.4. Kurapa kweaspergillosis kunokonzerwa neAspergillus fumigatus.5. Kugadzirira kwepamusoro kwakakodzera kune pigmented mycosis.Yakakodzerawo ganda fungal chirwere mushure mekupisa, kufema turakiti Candida uye Aspergillus kana cryptococcus utachiona, uyewo basa fungal corneal ulcer.
Zvinowanzoitika zvinosanganisira kupisa muviri, kupindwa nechando, uye kutemwa nemusoro nguva pfupi mushure mekunge mushonga wapihwa, pamwe nedambudziko reitsvo.Allergic zviratidzo zvinosanganisira anaphylaxis zvinogona kuitika.Mimwe migumisiro yakakomba inosanganisira yakaderera potassium yeropa uye kuzvimba kwemoyo.Zvinoita sokuti hazvina ngozi pamuviri.Pane lipid formulation ine njodzi yakaderera yemhedzisiro.Iri mukirasi ye polyene yemishonga uye inoshanda muchikamu nekupindira ne cell membrane yefungus.Inofanirwa kuve yekuchenjerera kushandiswa kana pakaitika mamiriro ezvinhu, nekuti kushandiswa kwekuchengetedza kunofanirwa kutevedzera zano revashandi vekurapa.
Tsanangudzo YeOral Giredhi (Mumba Standard)
| Item | Tsanangudzo |
| Chitarisiko | Yero kusvika kuorenji-yero hupfu, isinganhuhwi kana inenge isinganhuhwi. |
| Identification | IR, HPLC |
| pH | 4.0-6.0 |
| Kurasika paKuomesa | ≤5.0% |
| Sulfated Ash | ≤3.0% |
| Related Substances | ≤0.5% |
| 303nm | Kusachena A (Amphotericin A) ≤5.0% Kusachena kusingazivikanwe kwemunhu ≤1.0% |
| 383nm | Kusachena B (Amphotericin X1) ≤4.0% Kusachena kusingazivikanwe kwemunhu ≤2.0% |
| Zvose Zvisina Kuchena | ≤15.0% |
| Residual solvents | Methanol ≤0.3% Acetone ≤0.5% |
| Assay | ≥850 amphotericin B mayunitsi/mg yezvinhu zvakaomeswa. |
Tsanangudzo YeOral Giredhi (Mumba Standard)
| Item | Tsanangudzo |
| Chitarisiko | Yero kusvika kuorenji hupfu husina kunhuhwirira. |
| Identification | IR, HPLC |
| Residue pakubatidza | ≤0.5% |
| Zvinhu zvinoenderana |
|
| 303nm | Amphotericin A ≤2.0% |
| Kusachena kwemunhu kusingazivikanwe ≤1.0% | |
| 383nm | Amphotericin X1 ≤4.0% |
| Kusachena kusingazivikanwe kwemunhu ≤2.0% | |
| Zvose zvisina kuchena | ≤15.0% |
| Residual solvents | Acetone ≤0.5% |
| Methanol ≤0.3% | |
| Microbiological limit | Aerobic microbial count ≤1000cfu/g |
| Molds & yeasts ≤100cfu/g | |
| Escherichia coli Kushaya mu1g | |
| Bacterial endotoxins | <1.0EU/mg |
| Assay | ≥850 amphotericin B mayuniti / mg, akaverengerwa pane yakaomeswa hwaro |
