Pharmaceutical production quality management standard (GMP) yatinoziva, kusanganisirwa zvishoma nezvishoma kweEHS muGMP, ndiyo yakajairika.
Iyo musimboti weGMP, haingodi chete chigadzirwa chekupedzisira kuti chisangane nemhando yemhando, asiwo iyo yese yekugadzira maitiro inofanirwa kusangana nezvinodiwa zveGMP, iyo process tekinoroji manejimendi, batch / batch nhamba manejimendi, kuburitsa uye zvinhu chiyero chekuongorora, hutano manejimendi, chitupa manejimendi, kutsauka manejimendi sekutarisa.Kune chero maitiro anokanganisa zvinhu zvikuru zvemhando yechigadzirwa (man-machine material ring) kutora marudzi ese ematanho anobatsira kudzivirira kusvibiswa uye kusvibiswa kwemuchinjiko, kuvhiringidzika uye kukanganisa kwevanhu, kuve nechokwadi chekuchengetedzwa kwekugadzirwa kwezvinodhaka, kuve nechokwadi chemhando ye zvinodhaka.Muna Chivabvu 2019, WHO yakaburitsa Mamiriro Ezvakatipoteredza eZVAKANAKA Kugadzira Maitiro: Mafungiro kune Vagadziri uye Inspectors mukudzivirira kwekudzivirira kwemishonga inorwisa mabhakitiriya, kusanganisira marara uye kurapwa kwemvura yetsvina seGMP yekutarisa.Nyaya yekuchengetedzwa kwevashandi inonziwo ichanyorwa muGMP itsva.Occupational exposure level (OEB) dziviriro, inofanirwa kukonzera kutarisisa kwemabhizinesi emishonga!
Njodzi dzepabasa dzinokonzerwa nemishonga inoshanda zvinosanganisa (API) ndiwo akakosha uye akaoma mapoinzi ekudzivirira njodzi yebasa uye manejimendi ekutonga mumabhizinesi emishonga.Zvichienderana nenjodzi, mishonga mitsva yakawanda uye mishonga inoshanda zvikuru, yakadai semishonga yekenza uye penicillin, inokwezva kutariswa, asi mishonga yemagetsi haikweveri zvakanyanya kumba nekune dzimwe nyika.Chinonyanya kuoma ndechekuti "industrial hygiene (IH)" kukosha kwechinhu chinoshanda chakaoma kuziva uye chinoda kutanga kubva kune toxicology uye kiriniki.OEB yekudzora nhanho inowanzoiswa giredhi zvinoenderana neMSDS yemubvunzo mhedzisiro yemakomponi.Kana iwe ukashandisa zvinodhaka zvitsva, ungada kushandisa mari yako uye simba kuita zvinoenderana necompound chiitiko chekuongorora;Pamishonga yegeneric, miganho uye mamakisi eOEL/OEB anogona kuwanikwa nekubvunza ruzivo rweMSDS rwekomboni.Related engineering control matanho anowanzo kukamurwa kuita: 1. Open operation;2. Kushanda kwakavharwa;3. Kupiwa kwemhepo yose;4. Kupera kwepanzvimbo;5. Kuyerera kwelaminari;6. Isolator;.
Mabhizinesi emudzimba emishonga anofanirwa kusimbisa kuchengetedza kwevashandi veEHS uye kuunza michina yekugadzira ine API OEB giredhi inoenderana.Zvakakodzera kutora zvidzidzo kubva kune vamwe vatengesi vemidziyo yekuEurope nekuAmerica vakaita zvakanaka mukudzivirira kwevashandi vavo, zvinoda mafaera eMSDS anowirirana uye kuchengetedzwa kunoenderana kunoreva magwaro ekugadzirira ezvigadzirwa zvebvunzo.Munguva yakapfuura, apo mabhizinesi emishonga emudzimba aigadzira zvigadzirwa zvakasiyana-siyana zvakadai seaneshesia yakanaka uye kusunungurwa kwetoxin, kudzivirira kweOEB kwakanga kusipo, izvo zvakaita kuti hutano hwevashandi vakawanda vepamberi huve hwakakanganiswa.Pasi pemamiriro ezvinhu ekuti kuzivikanwa kwepamutemo kwevashandi kwakasimbiswa zvishoma nezvishoma, mabhizinesi haaigona kupukunyuka mutoro wenjodzi dzinoenderana dzebasa.
Kuburikidza nekuongororwa kwengozi yeAPI, iyo calculation formula ye occupational exposure limit (OEL) inopiwa, API hazard classification system PBOEL inotangwa, uye mitemo yakawanda inofanira kuteverwa yekudzivirira nekudzivirira matanho anoiswa mberi.Mune ramangwana, isu tichaongorora chirongwa chekutonga zvakadzama.Ramba wakatarisa!
Nguva yekutumira: Kubvumbi-12-2022