Posaconazole 171228-49-2 Antibiotic
Kubhadhara:T/T, L/C
Kwakabva Chigadzirwa:China
Shipping Port:Beijing/Shanghai/Hangzhou
Kukwanisa kugadzira:20kg/mwedzi
Order(MOQ):10g
Nguva Yekutungamira:3 Mazuva Ekushanda
Mamiriro ekuchengetedza:Kuchengetwa munzvimbo inotonhorera, yakaoma, tembiricha yekamuri.
Package zvinhu:vial
Pakeji saizi10g/mudziyo
Mashoko ekuchengetedza:Kwete zvinhu zvine ngozi
Nhanganyaya
Posaconazole inonzi triazole antifungal mishonga.
Posaconazole inoshandiswa kurapa invasive Aspergillus uye Candida zvirwere.Inoshandiswawo pakurapa oropharyngeal candidiasis (OPC), kusanganisira OPC refractory kune itraconzaole uye / kana fluconazole therapy.
Inoshandiswawo kurapa zvirwere zvinopinda neCandida, Mucor, uye Aspergillus mhando muvarwere vasina kudzivirirwa zvakanyanya.
Tsanangudzo (mumba chiyero)
| Item | Tsanangudzo |
| Chitarisiko | Ichena kana inenge yakachena, hygroscopic powder |
| Item | Tsanangudzo |
| Chitarisiko | Ichena kana isina-white crystalline powder |
| Kutenderera chaiko | -28.0°~-34.0° |
| Crystal fomu | Inofanirwa kunge iri crystalline Ⅰ, iine 2-theta angles ye 14.4±0.2°,19.2±0.2°,21.7±0.2°,24.3±0.2°29.3±0.2° |
| Identification | IR, HPLC |
| Zvinoenderana zvinhu I | PO-R1 NMT 0.10% |
| PO-R2 NMT 0.10% | |
| PO-R3 NMT 0.10% | |
| PO-R4 NMT 0.10% | |
| PO-D3 & PO-D5 NMT 0.10% | |
| PO-D7 & PO-D10 NMT 0.10% | |
| Imwe neimwe yekusachena isina kutaurwa NMT 0.10% | |
| Zvose zvisina kuchena NMT 0.5% | |
| Zvinoenderana zvinhu Ⅱ | PO-E NMT 0.10% |
| PO-D1 NMT 0.10% | |
| PO-R5 NMT 0.10% | |
| Residual solvents | Methanol NMT 3000ppm |
| Ethanol NMT 5000ppm | |
| Dichloromethane NMT 600ppm | |
| Tetrahydrofuran NMT 720ppm | |
| N, N-dimethyl formamide NMT 880ppm | |
| Triethylamine NMT 100ppm | |
| Dimethy sulfoxide NMT 5000ppm | |
| Mvura | NMT 2.0% |
| Residue pakubatidza | NMT 0.1% |
| Heavy metals | NMT 10ppm |
| Microbial muganhu | Total aerobic NMT 1000cfu/g Yeasts ne molds NMT 100cfu/g E.coli inofanira kunge isipo |
| Assay | 98.0% -102.0% (pane anhydrous basis) |
| 98.0% -102.0% (pane anhydrous uye solvents yemahara base) |
