Tacrolimus monohydrate 109581-93-3 Antibiotic
Kubhadhara:T/T, L/C
Kwakabva Chigadzirwa:China
Shipping Port:Beijing/Shanghai/Hangzhou
Kukwanisa kugadzira:1kg/mwedzi
Order(MOQ):1g
Nguva Yekutungamira:3 Mazuva Ekushanda
Mamiriro ekuchengetedza:Kuchengetwa munzvimbo inotonhorera, yakaoma, tembiricha yekamuri.
Package zvinhu:vial, bhodhoro
Pakeji saizi1g/bhodhoro, 5/mubhodhoro, 10g/mubhodhoro, 50g/bhodhoro, 500g/bhodhoro
Mashoko ekuchengetedza:UN 2811 6.1/PG 3
Nhanganyaya
Tacrolimus, mushonga unodzivirira muviri.Mushure mekunge allogeneic organ transplant, njodzi yekurambwa kwenhengo ine mwero.Kudzikisa njodzi yekurambwa kwenhengo, tacrolimus inopiwa.Mushonga uyu unogona zvakare kutengeswa semushonga wepamusoro mukurapa T-cell-mediated zvirwere zvakaita seeczema uye psoriasis.Inogona kushandiswa kurapa yakaoma eye syndrome mumakati nembwa.
Tacrolimus inhibits calcineurin, iyo inobatanidzwa mukugadzirwa kwe interleukin-2, molecule inokurudzira kukura uye kupararira kweT masero, sechikamu chemuviri wakadzidza (kana adaptive) mhinduro yekudzivirira.
Tsanangudzo (USP43)
| Item | Tsanangudzo |
| Chitarisiko | Ichena kana inenge yakachena crystalline powder |
| Identification | IR, HPLC |
| Solubility | Yakanyanya kunyungudika mumethanol, inonyungudika zvakasununguka muN, N dimethylformamide uye mudoro, inonyungudika mumvura. |
| Residue pakubatidza | ≤0.10 % |
| Organic tsvina (maitiro-2) | Ascomycin 19-epimer ≤0.10 % |
| Ascomycin ≤0.50 % | |
| Desmethyl tacrolimus ≤0.10 % | |
| Tacrolimus 8-epimer ≤0.15 % | |
| Tacrolimus 8-propyl analogi ≤0.15 % | |
| Kusachena kusingazivikanwe -I ≤0.10 % | |
| Kusachena kusingazivikanwe -II ≤0.10 % | |
| Kusachena kusingazivikanwe -III ≤0.10 % | |
| Yese tsvina ≤1.00 % | |
| Optical kutenderera (sezvazviri) (10mg/ml in N,Ndimethylformamide) | -110.0° ~ -115.0° |
| Zvemumvura (neKF) | ≤4.0% |
| Residual solvents (neGC) | Acetone ≤1000ppm (Mumba) |
| Di-isopropyl ether ≤100ppm (Mumba) | |
| Ethyl ether ≤5000ppm | |
| Acetonitrile ≤410ppm | |
| Toluene ≤890ppm | |
| Hexane ≤290ppm | |
| Microbial test (mumba) | Total aerobic microbial count ≤100cfu/gm |
| Yese mbiriso uye mold kuverenga ≤10cfu/gm | |
| Zvisikwa zvakatsanangurwa (Zvirwere zvehutachiona) (E.coil, salmonella sps., S.aureus. Pseudomonas aeruginosa) hazvifanirwe kunge zvisipo. | |
| Assay (neHPLC) (pane anhydrous uye solvent yemahara base) | 98%~102% |
