Tulathromycin 217500-96-4 Antibiotic Antifungal
Kubhadhara:T/T, L/C
Kwakabva Chigadzirwa:China
Shipping Port:Beijing/Shanghai/Hangzhou
Kukwanisa kugadzira:400kg / mwedzi
Order(MOQ):25kg
Nguva Yekutungamira:3 Mazuva Ekushanda
Mamiriro ekuchengetedza:Kuchengetwa munzvimbo inotonhorera, yakaoma, tembiricha yekamuri.
Package zvinhu:ngoma
Pakeji saizi25kg / chigubhu
Mashoko ekuchengetedza:Kwete zvinhu zvine ngozi
Nhanganyaya
Tulathromycin, i-broad-spectrum antibacterial agent ine antibacterial activation kurwisa mamwe mabhakitiriya e gram-positive uye Gram-negative.Iyo inonyanya kunetseka kune hutachiona hwezvirwere zvekufema mumombe nenguruve, senge Actinobacillus pleuropneumoniae, Pasteurella haemolyticus, Pasteurella haemorrhagica, histophilus hope (Haemophilus kurara), Mycoplasma pneumoniae, Haemophilus parasuis, Bordetella bronchiseptica, nezvimwe.
Iyo pharmacokinetic maitiro eTulathromycin ndeyekuti mushure mekutonga kwedosi imwe chete, inokurumidza kunyura panzvimbo yejekiseni, iyo inoshanda yeropa inochengeterwa kwenguva yakareba, kubviswa kunonoka, vhoriyamu yekugovera inooneka yakakura, bioavailability yakakwira, uye iyo concentration muperipheral tissue yakakwira kudarika iri muplasma.Kupararira kwematishu kwakakura uye kunaka kwesero permeability zvinhu zvakakosha zveTulathromycin metabolism.Kuunganidza mumasero ekudzivirira muviri chinhu chakakosha cheTulathromycin.
Tulathromycin inhibits bhakitiriya mapuroteni synthesis nekuvhara bhakitiriya peptide kutamisa maitiro.Nekuda kwekukanganisa kwakakosha kwe erythromycin, vanhu vanoda mumwe mushonga panzvimbo yeerythromycin nekukurumidza.Tulathromycin rudzi rutsva rwemacrolide semi synthetic antibiotic yemhuka.Iyo ine zvakawanda zvakanaka, senge yakaderera dosage, imwe-nguva kutonga, yakaderera yasara, mhuka chaiyo uye zvichingodaro.Haisi chete ine zvakanakira macrolide zvinodhaka, asiwo ine ultra refu hafu yeupenyu iyo yakakwirira kune mamwe macrolide antibiotics.Zvichienderana nemukana wekuchengetedza unoshanda kurapa kusungwa mumuviri kwenguva yakareba, inogona kuwana zvirinani bacteriostasis uye sterilization.
Mushure mekushandiswa kwakawanda kwekiriniki, tulathromycin ine mhedzisiro yekurapa pazvirwere zvekufema zvemombe nenguruve.Tinotenda neakanakisa antibacterial chiitiko cheTulathromycin senge diki dosi uchishandisa, refu hafu yehupenyu uye imwe-nguva kutonga, inogona kushandiswa zvakanyanya.
Tulathromycin yakasimba kudarika macrolides anoshandiswa zvakanyanya pamusika parizvino, senge tylosin, tilmicosin uye florfenicol.Iyo ine yakakura inogona kushandiswa.
Cherechedza kuti Tulathromycin yakachengeteka, isina carcinogenicity, teratogenicity uye genotoxicity.Izvo hazvizokonzerese gene mutation, asi inogona kuburitsa cardiotoxicity.Inofanirwa kutevera mazano eveterinary.
Tsanangudzo (In House Standard)
| Item | Tsanangudzo |
| Chitarisiko | Muchena kana hupfu hunenge huchena |
| Solubility | Inonyungudika zvakasununguka mumethanol, acetone, uye methyl acetate, inonyungudika mu ethanol. |
| Specific optical rotation | -22° kusvika -26° |
| Identification | HPLC: nguva yekuchengeta yepamusoro peak muchromatogram yeassay kugadzirira inoenderana neiyo muchromatogram yestrandard gadziriro yakawanikwa sezvakatsanangurwa muyedzo. IR: IR spectrum inoenderana neCRS |
| Mvura | ≤2.5% |
| Residue pakubatidza | ≤0.10% |
| Heavy metals | ≤20ppm |
| Related substance | Kusachena kwese ≤6.0% Kusachena kwemunhu ≤3.0% |
| Bacterial endotoxin | <2 EU |
| Assay (anhydrous substance) | 95%-103% |
| Residual solvent | N-Heptane≤5000ppm Dichloromethane ≤600ppm |
| Assay | Zviri mukati C41H79N3O12: 95% -103% (Pane Anydrous substance) |
